Current Indications for Intraarterial Chemotherapy in Neurointerventional Surgery

Background In pursuit of a cure for cancer, it is imperative to utilize every tool, resource, and strategy. Included under this umbrella the optimization drug delivery. Broadly speaking, anti‐cancer treatment has been perpetually hindered by off‐target activity, systemic toxicity, other adverse reactions. Intraarterial (IA) delivery therapeutics an approach that garnered increased attention in recent years. This can deliver directly desired site with potential minimize toxicity. Methods review, we briefly cover existing IA indications peripheral solid tumors as base from which learn, followed trials procedural considerations neck, head, central nervous system tumors. Results While bulk research clinical have focused on outside system, there encouraging results tumor within neurointerventional arena, such head neck tumors, retinoblastoma, glioblastoma multiforme, lymphoma. Conclusion review highlights need chemotherapeutic multi‐disciplinary involving surgeons.